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An article published in the Journal of Controlled Release details the results of a cross-border scientific collaboration that has developed an alternative for the treatment of solid tumors based on inhibition of the inflammatory tumor microenvironment (TME). Solid tumors are difficult to treat, partly owing to cells and substances in the TME that prevent drugs from penetrating and stop the patient's own immune system from combating the tumor. "These cells and [...]

Researchers at the University of São Paulo (USP) in Brazil have demonstrated for the first time that SARS-CoV-2, the virus responsible for COVID-19, can persist in sperm for up to 90 days post-hospital discharge and up to 110 days after initial infection, reducing semen quality. These findings suggest that individuals planning to conceive should consider a "quarantine" period post-recovery. Covid invades the reproductive system Four years into the pandemic, it is [...]

Amolecule produced naturally in the gut can help prevent and even treat influenza, according to a study reported in the journal Gut Microbes by researchers at the State University of Campinas (UNICAMP) in São Paulo state, Brazil, and Pasteur Institut in Lille, France. Experiments with mice showed a fall in levels of the molecule indole-3-propionic acid (IPA) during infection by influenza virus H3N2. The infected animals' IPA was supplemented with a synthetic version of the [...]

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that SARS-CoV-2, the virus that causes COVID-19, can remain in the sperm of patients for up to 90 days after hospital discharge and up to 110 days after the initial infection, reducing semen quality. The study is reported in an article published in the journal Andrology. The authors suggest that people who plan to have children should observe a period of "quarantine" after [...]

An article published in the journal Insects determines with precision the dispersal range of a type of wasp that neutralizes the brown stink bug, Euschistus heros, a major soybean pest in Brazil and one that is highly resistant to chemical insecticides. The solution discussed by the authors is Telenomus podisi, a parasitoid microwasp first described by American entomologist William Harris Ashmead in 1893. Parasitoids are small insects whose immature stages develop either within or attached [...]

An article published in the journal Polymer describes the production of a material with the potential to be used to obtain hydrogen (H2) by solar-driven water splitting (photoelectrocatalysis) instead of the conventional electricity-driven process. Also known as green hydrogen, H2 produced from renewable sources is a strong candidate for the accolade "fuel of the future." The article describes the preparation of films comprising polyaniline nanostructures with an underlayer of [...]

Anti-obesity drugs such as Ozempic were the "breakthrough of the year" in 2023, according to the AAAS journal Science. Overweight and obesity rates are rising worldwide, with several Latin American countries in the forefront. Estimates for 2020 pointed to a global obesity rate of 14%, and experts predicted 24% by 2035, including both adults and children. "Nutritional and pharmacological strategies are important to mitigate the problem, but is this enough? We know socioeconomic [...]

Recent research published in the journal Clinical Nutrition reveals a significant link between high consumption of ultra-processed foods and an increased risk of developing depression. This study, conducted in Brazil, indicates that individuals adhering to diets rich in ultra-processed foods are more likely to experience depressive symptoms over time. These findings underscore the potential mental health risks associated with dietary patterns characterized by processed and convenience [...]

A study conducted by researchers at the University of São Paulo (USP) in Brazil and reported in an article published in Nature Communications shows that the Cerrado, Brazil's savanna biome, is experiencing the worst drought for at least 700 years. Here's why. The effects of global warming have been particularly intense in the central region of the country, where the rise in temperatures is about 1 °C higher than the 1.5 °C global average. This has [...]